
The difficulty with generating vaccines or therapeutic antibodies against rhinoviruses is that there are 102 accepted, classified serotypes with potentially more that have yet to be classified. Despite the multitude of serotypes, all rhinoviruses interact with ICAM-1 implying some conserved functional motif that is not targetable via conventional approaches. BMI’s Immune Dampening and Refocusing Technology can address the multiple serotype issue such that broadly reactive immune responses and therapeutic antibodies can be made. BMI’s rhinovirus program parallels its veterinary program in Foot and Mouth Disease Virus, a highly related picornavirus.